東京ビジネスクリニック

COVID19_Vaccine

This document contains important information regarding the COVID-19 vaccine.

The vaccine administered this time is manufactured by Pfizer. It helps prevent the onset of COVID-19.

Product Name

COMIRNATY RTU Intramuscular Injection (Single-dose vial)

Efficacy and Indications

Prevention of infections caused by SARS-CoV-2

Eligible Recipients

[Pediatric Use] Ages 5–11
[Adult Use] Ages 12 and above

Dosage

0.3 mL per dose

Price¥17,500
(¥19,250 tax included)

※This service is available by phone reservation only.

※Even after vaccination, it is necessary to continue taking appropriate infection prevention measures.

People who fall under the following categories cannot receive this vaccine.
If you think any of these apply to you, please be sure to inform your doctor during the pre-vaccination consultation.

  • People who have an obvious fever (Note 1) or are suffering from a serious acute illness
  • People with a history of severe hypersensitivity (Note 2) to any component of this vaccine
  • People who, for other reasons, are considered unsuitable for vaccination

(※1) A clear fever is generally defined as a body temperature of 37.5°C or higher. However, even if the temperature is below 37.5°C, it may still be considered a fever depending on the person’s usual baseline temperature.
(※2) Symptoms suggestive of anaphylaxis include anaphylactic reactions or multiple systemic symptoms such as widespread skin and mucosal manifestations, wheezing, difficulty breathing, rapid heartbeat, and low blood pressure.

People Who Should Take Precautions Before Receiving This Vaccine

If any of the following apply to you, please be aware that special caution may be needed when receiving this vaccine. If you think any of these conditions may apply, be sure to inform your doctor during the pre-vaccination consultation.

  • People who are undergoing anticoagulant therapy, or who have thrombocytopenia or bleeding disorders
  • People who have been diagnosed with immunodeficiency in the past, or who have close relatives with congenital immunodeficiency
  • People with underlying medical conditions such as heart, kidney, liver, blood disorders, or developmental disorders
  • People who experienced suspected allergic reactions such as fever or widespread rash within two days after a previous vaccination
  • People who have had seizures in the past
  • People who may be allergic to any component of this vaccine
  • People with impaired kidney function
  • People with impaired liver function

If you are pregnant, may be pregnant, or are breastfeeding, please be sure to inform your doctor during the pre-vaccination consultation.

This vaccine contains adjuvants that have not been used in previous vaccines.

If you have ever experienced hypersensitivity or allergic reactions to medications in the past, you must inform your doctor during the consultation before vaccination.

  • After receiving the vaccine, please stay at the vaccination site for at least 15 minutes.
  • If you have experienced severe allergic reactions such as anaphylaxis, or have ever felt unwell or fainted after a vaccination, please remain for at least 30 minutes.
  • If you feel any unusual symptoms, contact a doctor immediately. (This allows for prompt treatment of sudden adverse reactions.)
  • Keep the injection site clean. Bathing on the day of vaccination is allowed, but do not rub the injection area.
  • You may continue your usual daily activities, but please refrain from intense physical exercise or excessive alcohol consumption on the day of vaccination.

The main side effects include pain at the injection site, headache, joint and muscle pain, fatigue, chills, and fever. In rare cases, serious side effects such as shock or anaphylaxis may occur. Since this is a new type of vaccine, there may be symptoms that have not yet been identified. If you experience any concerning symptoms after vaccination, please consult the administering doctor or your primary care physician.

Although extremely rare, mild cases of myocarditis or pericarditis have been reported after vaccination (*). If you experience symptoms such as chest pain, palpitations, shortness of breath, or swelling within a few days after vaccination, seek medical attention immediately.

(*) These cases are more common after the second dose than the first, and tend to occur more frequently in young people, especially males.

In rare cases, vaccination may cause health problems such as illness or lasting disabilities. Although such cases are extremely uncommon, they cannot be entirely eliminated, which is why a relief system has been established.

This vaccine is a messenger RNA (mRNA) vaccine that contains mRNA encoding the spike protein of SARS-CoV-2 (a protein necessary for the virus to enter human cells), encapsulated in a lipid nanoparticle. Once administered, the mRNA is taken up into human cells, where it directs the production of the viral spike protein. This, in turn, induces the production of neutralizing antibodies and a cellular immune response against the spike protein, thereby helping to prevent infection caused by SARS-CoV-2.

This product contains the following ingredients.

Active IngredientBNT162b2 (also known as Tozinameran or Comirnaty)
Additives
  • ALC-0315: ((4-hydroxybutyl) azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)
  • ALC-0159: 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide
  • DSPC: 1,2-distearoyl-sn-glycero-3-phosphocholine
  • Cholesterol
  • Purified Sucrose
  • Tromethamine
  • Tromethamine Hydrochloride
Active Ingredient

BNT162b2 (also known as Tozinameran or Comirnaty)

Additives
  • ALC-0315: ((4-hydroxybutyl) azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)
  • ALC-0159: 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide
  • DSPC: 1,2-distearoyl-sn-glycero-3-phosphocholine
  • Cholesterol
  • Purified Sucrose
  • Tromethamine
  • Tromethamine Hydrochloride

Our clinic provides information related to COVID-19.